Annie Worthing, who voiced Tess in The Last of Us (opens in new tab) and appeared in numerous television series during her 20-year career, has died of cancer at age 45.

Deadline (opens in new tab) reports that Worthing was diagnosed with cancer in 2020, but continued to appear in several popular shows. One of her last roles was as the Borg Queen in six episodes of the second season of Star Trek: Picard, 20 years after she first appeared on television in an episode of Star Trek: Enterprise.

According to Wersching's IMDB page (opens in new tab), her final credit concludes her multi-season run on Nathan Fillion's popular series "The Rookie," in which she also appeared in "Bosch," "Runaways," Timeless," "The Vampire Diaries," and "24," where she also had regular appearances. She has also appeared regularly on "Bosch," "Runaways," "Timeless," "The Vampire Diaries," and "24."

However, to gamers, she is best known for her role as Tess Servopoulos, Joel's partner and a key supporting character in the original version of The Last of Us; Anna Torv plays Tess in HBO's TV version of The Last of Us.

Neil Drachman, co-creator of The Last of Us, paid tribute to Wersching on Twitter. 'Just learned of the passing of my dear friend Annie Wersching. 'We have lost Annie, a beautiful artist and human being. My heart is shattered. I am with her loved ones."

Drachman also linked to a GoFundMe campaign for Wersing's three children.

Naughty Dog, the studio behind The Last of Us, also said it was "deeply saddened to hear the news of Annie Wersching's passing."

"There is a gaping hole in the soul of this family today. But she left us with the tools to fill it," Wersching's husband Stephen Full said in a statement. 'She found wonder in the simplest of moments. She didn't need music to dance. She taught us not to wait for adventure to find you. Go find it. It is everywhere. And we will find it."

Other tributes to Wersching's life and career came from Kiefer Sutherland of "24," who described her as "one of the greatest actors I've ever had the pleasure of working with," and the official Paramount Plus "Star Trek" account.

Five years after playing Tess in The Last of Us, she also appeared as Tashin in EA's 2019 sci-fi game Anthem.